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Compositions comprising viruses and methods for co

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专利名称:Compositions comprising viruses and

methods for concentrating viruspreparations

发明人:Frei, Andreas,Kwan, Henry,Sandweiss, Varda

E.,Vellekamp, Gary J.,Yuen, Pui-Ho,Bondoc,Laureano L., Jr.,Porter, FrederickWilliam,,Tang, John Chu-Tay,Ihnat, Peter

申请号:EP04030395.0申请日:19990212公开号:EP1526174B1公开日:20070822

摘要:Methods for purifying virus preparations are disclosed comprising (a) subjectinga virus preparation to anion-exchange chromatography, (b) adding a polyhydroxyhydrocarbon to the virus preparation of step (a), (c) increasing the concentration of virusin the virus preparation product of step (b) by applying pressure to the preparation suchthat diluent is removed from the virus preparation through a filter, and (d) subjecting theconcentrated virus preparation product of step (c) to one or more additional processingsteps.

申请人:SCHERING CORP

地址:US

国籍:US

代理机构:Naylor, Kathryn May

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