Method and kit for detection of hemolytic uremic s

专利名称：Method and kit for detection of hemolytic

uremic syndrome and necrotizing

pneumonia in children with pneumococcaldisease using serum fetuin-A levels as abiomarker

发明人：Cheng-Hsun Chiu,Rajendra Prasad

Janapatla,Chyi-Liang Chen

申请号：US14497989申请日：20140926公开号：US09261504B1公开日：20160216

摘要：The invention provides a method and a kit for measuring the levels of serumfetuin-A in children to reflect the severity of invasive pneumococcal diseases caused by ,including necrotizing pneumonia and hemolytic uremic syndrome. The mean fetuin-Alevels in the HUS patients are significantly lower (207±80 mg/L, p<0.001) when comparedto patients with lobar pneumonia (610±190 mg/L) and the healthy controls (630±250mg/L). A serum fetuin-A level is a useful biomarker to classify the severity of

pneumococcal infection in children. The level of biomarker fetuin-A can be monitored andevaluated by enzyme linked immunosorbent assay and Western blot hybridization.

申请人：Cheng-Hsun Chiu,Rajendra Prasad Janapatla,Chyi-Liang Chen

地址：Taoyuan County TW,Taoyuan County TW,Taoyuan County TW

国籍：TW,TW,TW

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