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NOVEL TARGETED COMPOSITIONS FOR DIAGNOSTIC AND THE

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专利名称:NOVEL TARGETED COMPOSITIONS FOR

DIAGNOSTIC AND THERAPEUTIC USE

发明人:UNGER, Evan, C.,MCCREERY, Thomas, P.申请号:EP03732069.4申请日:20030123公开号:EP1478276A2公开日:20041124

摘要:Novel targeted compositions which may be used for diagnostic and therapeuticuse. The compositions may comprise lipid, protein or polymer gas-filled vesicles whichfurther comprise novel compounds of the general formula L-P-T, wherein L comprises ahydrophobic compound, P comprises a hydrophilic polymer, and T comprises a targetingligand which targets tissues, cells or receptors, including myocardial cells, endothelialcells, epithelial cells, tumor cells and the glycoprotein GPIIbIIIa receptor. The

compositions can be used in conjunction with diagnostic imaging, such as ultrasound, aswell as therapeutic applications, such as therapeutic ultrasound.

申请人:Imarx Therapeutics, Inc.

地址:1635 E. 18th Street Tucson, AZ 85719 US

国籍:US

代理机构:Hallybone, Huw George

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