Product Name:CAS No.: Cat. No.:MWt:Formula:Purity :
Mc-Val-Cit-PABC-PNP159857-81-5HY-20336737.76C35H43N7O11>98%
Solubility:DMSO > 42 mg/ml
Mechanisms:
Pathways:Antibody-drug conjugates/ADCs Related; Target:ADCs linker
Biological Activity:
Mc-Val-Cit-PABC-PNP is a cathepsin cleavable ADC peptide linker. For example, FDA approved drug,brentuximab vedotin, adopts this linker.
References:
[1]. Anti-cd70 antibody-drug conjugates and their use for the treatment of cancer and immune disorders
Caution: Not fully tested. For research purposes only
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